Week 6 NFL Survivor Picks Strategy & Advice (2025)

We run through the most popular NFL Survivor picks for Week 6 plus strategy insights and updates throughout the week.

by Jason Lisk - Oct 12, 2025

We’re back with our Week 6 NFL Survivor picks and strategy column, the weekly companion to our NFL Survivor Picks product. While the product gives personalized recommendations based on your specific pool size and rules, this column zooms out to cover broader strategy, key decision points, and the week-to-week dynamics shaping the survivor landscape.

Week 5 was pure carnage. Between the Cardinals’ collapse, the Rams’ overtime loss, and the Bills’ loss on Sunday night, it was the first true wipeout week of the season — we estimate that standard NFL Survivor pools were cut roughly in half.

So if you’re still standing heading into Week 6, congrats — you made it through one of the wildest weeks survivor pools have seen in years (with the worst NFL Survivor beat of all-time).

This week, we’ll break down how to play it now that the field has thinned out, run through the most popular picks, and give you a complete game plan for Week 6 NFL Survivor.

This article will be updated throughout the week with injury news, line movement, and shifts in pick popularity.

Here’s what we have so far:

• 10/12: Week 6 Sunday AM Pick Overview
• 10/10: Week 6 Survivor Strategy Breakdown
• 10/9: Colts Rise with Kyler Concerns, and Eagles Start Week on TNF
• 10/8: Green Bay: High Win Odds, but How Do You Like Your EV?
• 10/8: NFL Survivor Video: Week 6
• 10/7: Five Most Popular Survivor Picks (Week 6)
• 10/7: PoolGenius Survivor Bowl Status
• 10/7: Week 5 Recap
• FYI: About Our Survivor Advice

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Sunday 10/12

Week 6 Sunday AM Pick Overview

Here’s how our customized subscriber pick recommendations stand as of Sunday at 8:30 AM ET, comparing public picking trends to the percentage of picks we’re recommending to PoolGenius subscribers (the “PoolGenius” column).

The last seven columns in the table show how our recommended picks vary by subscriber pool format/rules (we added late start data to the table this week). The table shows every team with at least 2% public popularity and/or is drawing at least one recommendation from PoolGenius to one of your pool entries.