Video: NFL Week 5 Survivor Picks & Tips (2025)

Stephen Andress and Jason Lisk both won major NFL Survivor contests last season, and they are here to guide your Week 5 picks.

If you’re looking for NFL Survivor Week 5 picks and strategy, you’re in the right place. The big question this week: Do you roll with the Arizona Cardinals as the likely most popular play, or pivot to other options with stronger future value?

Arizona is a 7.5-point home favorite over the winless Titans, but many players have already used them. That makes the decision even tougher: burn the Cardinals now in one of their last great spots, or look elsewhere?

The Detroit Lions and Indianapolis Colts also project as strong favorites, though Detroit carries some of the highest future value on the board. Meanwhile, the Buffalo Bills resurface as Sunday Night Football favorites, and the Rams could even be in play on Thursday night against the banged-up 49ers.

Inside the Week 5 NFL Survivor Pick Breakdown

In the video above, we cover everything you need to make smarter NFL Survivor picks for Week 5, including:

  • Win odds for all key teams and where the value lies

  • Projected pick popularity and how to pivot from the chalk

  • Future value considerations for teams like the Lions and Bills

  • Expected value (EV) comparisons to find the sharpest paths

  • Adjustments for large national contests vs. smaller home pools

Make Smarter NFL Survivor Picks

Want to follow the same process we reference in the video? PoolGenius is offering a 3-day free trial, giving you full access to the NFL Survivor Picks product.

With this tool, you can:

  • Enter your pool size and rules to get customized weekly pick recommendations

  • See how different teams grade out on win odds, popularity, and future value

  • Build a portfolio strategy if you’re running multiple entries, spreading risk while maximizing long-term upside

PoolGenius Free Trial Available for New Users

NFL Survivor Week 5 Insights

In addition to the video, Jason Lisk publishes a weekly article that digs deeper into NFL Survivor Week 5 strategy. His analysis breaks down popularity trends, leverage opportunities, and how to best manage your entries across the season.

Pairing this written analysis with the Survivor Tool gives you the full toolkit to make more informed picks and avoid common traps.

Final Thoughts on Week 5

Week 5 is shaping up as a pivotal slate. Do you burn the Cardinals in their best spot of the year, or lean on safer but more valuable teams like Detroit or Buffalo? These strategic calls separate entries still standing in December from those eliminated in October.

For more fundamental strategy tips, check out our article on How to Win Your NFL Survivor Pool.