Week 10 Football Pick’em Contest Strategy & Advice (2025)

Week 10 NFL pool pick’em strategy and advice covering public pick trends, top value plays, and where to find edges in game-winner and spread pools.

Green Bay Packers running back Josh Jacobs (8) scores a touchdown during a game between the Green Bay Packers and the Carolina Panthers at Lambeau Field on November 2, 2025 in Green Bay, WI.

(Photo by Larry Radloff/Icon Sportswire)

Welcome to our NFL Pick’em strategy article for Week 10. As always, this column pairs best with the Football Pick’em Picks tool, which blends public pick rates with advanced modeling to surface the smartest plays for your specific pool and rules.

Each week, we share value picks and how to approach risk/reward scenarios for NFL and college pick’em pools. We’ll explain the logic behind our calls, especially when a contrarian angle offers value.

We will keep this page updated with new insights, injury notes, market movement, and more.

Here is what you will find so far:

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Sunday, Nov. 9

Sunday Rooting Rundown

Our pick recommendations can be for different teams for different types of pools. What we recommend in a season-long can differ from what we recommend in a weekly contest, and spread pools can be a different beast. Even in spread pools, you may have a different pick recommendation than our general numbers, because of the specific numbers available in your pool.

This Week 10 rooting guide offers a general overview of our pick recommendations, and individual results may vary.

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